I do like Fusion but wouldn’t call it necessary to play. It was a polished 2d platformer in a period where not many games like that were being made. Fusion and Zero Mission both have a similar (and today common-ish) design philosophy of mostly linear forced paths across a nonlinear landscape, with very clear guideposts so that players cannot get lost. Personally I find this works just fine in Fusion which is a space station with a computer constantly locking doors to prevent an infection from spreading, but is really dissonant in Zero Mission which is ancient ruins where the Chozo inexplicably play the guiding/locking role.
If you’re itching to play a solid but nonnotable sci-fi platformer, you won’t regret playing Fusion, but in that case I recommend checking out Environmental Station Alpha first.