the biggest thing is bet hedging and planning with the corners and discard. before any of the multipliers you get at the end, the corner hand is worth x2 and the discard hand (which obvs requires getting every other hand) is x3.
im not brave enough to go for big swings on the discard hand yet cause you get so little control of it by nature so i mostly end up with trash like pairs in it, but i generally (spoiling just in case folks wanna entirely reach strategies on their own) try to start building the first half of a strong hand in the corners on the first deal because theyre the most important for setting the tone of how you play the other deals (and they overlap with half of the normal row/column hands so if you dont try to build the corners first you may end up without good hands to make in them) and then like. obviously the mults for getting more hands is big so a pair in some random hand is better than nothing in it. im generally sitting around 4-5k but ive managed to get into like 20k on a few occasions